Metabolic Reactions to Acidosis Produced by Ammonium Chloride
نویسندگان
چکیده
منابع مشابه
Metabolic Reactions to Acidosis Produced by Ammonium Chloride.
Acidosis is so frequently put forward as the underlying pathological condition in such a variety of disorders that it is important to appreciate what actually are the metabolic manifestations of the acidotic state. Clinically one seldom if ever has an opportunity of studying acidosis uncomplicated by some such other factor as inanition or toxaemia. It is therefore advisable in an investigation ...
متن کاملInduction of metabolic acidosis with ammonium chloride (NH4Cl) in mice and rats--species differences and technical considerations.
Ammonium chloride addition to drinking water is often used to induce metabolic acidosis (MA) in rodents but may also cause mild dehydration. Previous microarray screening of acidotic mouse kidneys showed upregulation of genes involved in renal water handling. Thus, we compared two protocols to induce metabolic acidosis in mice and rats: standard 0.28M NH(4)Cl in drinking water or an equivalent ...
متن کاملCorrection of thiazide hyperuricemia by potassium chloride and ammonium chloride.
Large doses of KCI lowered serum uric acid while producing mild, apparently unrelated, uricosuria in four chlorothiazide-treated subjects. In two control subjects KCI also caused mild uricosuria, but had a negligible effect on serum uric acid concentration. Ammonium chloride decreased serum urate in all six subjects, while urinary uric acid excretion remained essentially unchanged. It is sugges...
متن کاملDirect urine ammonium measurement in metabolic acidosis: time to move on.
To the editor: The case report by Tuchscherer and Rehman is indeed interesting. However, this article requires that we look more closely at what is meant by urinary ammonium being measured. The renal response to metabolic acidosis is to increase excretion of hydrogen ion in the form of ammonium; the measurement of its urinary concentration is important when trying to identify the cause of the a...
متن کاملFetal abnormalities produced after preimplantation exposure of mouse embryos to ammonium chloride.
BACKGROUND The aims of this study were to determine whether preimplantation exposure of mouse embryos to ammonium resulted in abnormal fetal development and to evaluate similar risks to the outcome of human assisted conception. METHODS Mouse embryos cultured from the 1-cell stage were exposed to 0.3 mmol/l ammonium chloride for 3 days. Embryos cultured from the 2-cell stage were exposed to 0....
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ژورنال
عنوان ژورنال: Archives of Disease in Childhood
سال: 1930
ISSN: 0003-9888,1468-2044
DOI: 10.1136/adc.5.27.207